We are investigating the mechanisms by which non-pathogenic microbes are able to colonize, multiply, and thrive inside plant leaves.
We mainly study the interaction between Arabidopsis and Pseudomonas syringae (Pst), although we have ventured into evaluating the colonization of plants by endogenous non-pathogenic microbiota. We also use tobacco and tomato plants for our research.
There are two main projects in the lab:
Understanding the mechanisms behind non-pathogenic microbiota survival and multiplication inside plants.
In planta colonization of commensal-simulating Pst ∆hrcC∆CFA at 5 days shows colonies that arose from new division (circled in magenta), and those that were static (circled in white) over the 5-day experiment.
Are virulent pathogens experiencing Effector-triggered immunity physiologically analogous to non-pathogenic microbiota?
We are also comparing the recognition of AvrPto in the Brassicaceae (Arabidopsis) and Solanaceae (tomato and tobacco), plant lineages that diverged over 100 million years ago.
By identifying the mechanisms behind bacterial survival and multiplication, we aim to use the knowledge to develop strategies to enhance colonization by beneficial microbiota strains and hamper colonization by pathogens, thereby increasing crop productivity.